Postdoctoral Researcher - MBI

e-mail: kbiswas (at) hbku.edu.qa

 

Integrated PhD: Indian Institute of Science, Bangalore, India

Laboratory: Prof. Sandhya S. Visweswariah, Department of Molecular Reproduction, Development and Genetics, Indian Institute of Science, Bangalore, India. Year 2011

 

Research interests: I'm interested in understanding the dynamics and mechanics of cell-cell junction formation and the role of protein clustering in the functioning of cell adhesion receptors and associated proteins. I engineer micro- and nano-patterned, supported lipid bilayer substrates to enable experiments related to cell adhesion and signaling.

 

Lab Website

 

CV

 

Highlighted publications:

[4] Biswas KH*, Hartman KL, Zaidel-Bar R*, Groves JT* (2016) Sustained α-catenin activation at E-cadherin junctions in the absence of mechanical force. Biophysical Journal 111, 1044-52

 

[3] Biswas KH#, Hartman KL#, Yu C-H, Harrison OJ, Song H, Smith AW, Huang WYC, Lin W-C, Guo Z, Padmanabhan A, Troyanovsky SM, Dustin ML, Shapiro L, Honig B, Zaidel-Bar R and Groves JT (2015) E-cadherin junction formation involves an active kinetic nucleation process. Proc. Natl. Acad. Sci. USA 112(35): 10932-7

 

[2] Biswas KH and Visweswariah SS (2011) Distinct Allostery Induced in the Cyclic GMP-binding, Cyclic GMP-specific Phosphodiesterase (PDE5) by Cyclic GMP, Sildenafil, and Metal Ions. J Biol Chem 286(10): 8545-54

 

[1] Biswas KH, Sopory S and Visweswariah SS (2008) The GAF domain of the cGMP-Binding, cGMP-specific phosphodiesterase (PDE5) is a sensor and a sink for cGMP. Biochemistry 47(11): 3534-43

*co-corresponding author

#co-first author