Groves Lab

Physical Chemistry in Living Systems

Full Publication List

See also: Google Scholar

 

- 2018 -

 

151.  Biophys. J. 2018 in press: “Spatiomechanical modulation of EphB4:ephrin-B2 signaling in neural stem cell differentiation”, Meimei Dong, Dawn P. Spelke, Young Kwang Lee, Jean K. Chung, Cheng-Han Yu, David V. Schaffer*, Jay T. Groves*.

 

150.  Langmuir 2018, in press: “Membrane reconstitution of monoamine oxidase enzymes on supported lipid bilayers”, Liulin Wang, Kabir H. Biswas, Bo Kyeong Yoon, Lisa M. Kawakami, Soohyun Park, Jay T. Groves, Lin Li, Wei Huang, and Nam-Joon Cho*.

 

149.  Langmuir 2018, in press: “Fabrication of multicomponent, spatially segregated DNA and protein functionalized supported membrane microarray”, Kabir H. Biswas*, Nam-joon Cho, and Jay T. Groves*.

 

148.  Cell 2018, 174, 672–687: “Isolation of a structural mechanism for uncoupling TCR signaling from peptide-MHC binding”, Leah V. Sibener, Ricardo A. Fernandes, Catherine Carbone, Elizabeth Moyanoru, Darren McAffee, Xinbo Yang, Laura Su, Wong Yu, Shen Dong, Marvin H. Gee, Kevin Jude, Michael E. Birnbaum, Mark M. Davis, Jay T. Groves, Brian Evavold, Ron Vale, K. Christopher Garcia*.

 

147.  Cell 2018, 174: 338-349: “mTORC1 controls phase separation and the biophysical properties of the cytoplasm by tuning crowding”, M. Delarue, G. P. Brittingham, S. Pfeffer, I. V. Surovtsev, S. Pinglay, K. J. Kennedy, M. Schaffer, J. I. Gutierrez, D. Sang, G. Poterewicz, J. K. Chung, J. M. Plitzko, J. T. Groves, C. Jacobs-Wagner, B. D. Engel, L. J. Holt*.

 

146.  Proc. Natl. Acad. Sci. USA 2018  115 (25) p E5696-E5705: “Spatially modulated ephrinA1:EphA2 signaling increases local contractility and global focal adhesion dynamics to promote cell motility”, Zhongwen Chen, Dongmyung Oh, Kabir H. Biswas, Cheng-Han Yu, Ronen Zaidel-Bar*, and Jay T. Groves*.

 

145. Adv. Biosys. 2018, 2, 1800015: “Multicomponent Supported Membrane Microarray for Monitoring Spatially Resolved Cellular Signaling Reactions”, Kabir H. Biswas,* Chen Zhongwen, Alok Kumar Dubey, Dongmyung Oh,  and Jay T. Groves*.

 

144.  Langmuir 2018, 34 (4): 1775-1782: “Interfacial forces dictate pathway of phospholipid vesicle adsorption onto silicon dioxide surfaces”, Kabir H. Biswas, Joshua A. Jackman, Jae H. Park, Jay T. Groves, and Nam-joon. Cho*.

 

143.  Biophys. J. 2018, 114: 137-145: “Membrane-reconstituted K-Ras4B remains monomeric over a wide range of surface densities and membrane lipid compositions”, Jean K. Chung, Young Kwang Lee, John-Paul Denson, William K. Gillette, Steven Alvarez, Andrew G. Stephen, and Jay T. Groves*.

 

142.  Curr. Op. Cell Biol. 2018, 51: 97-102: “EGFR family and Src family interactions: mechanics matters?”, Z. Chen, D. Oh, A.K. Dubey, M. Yao, B. Yang, J.T. Groves, and M. Sheetz.

 

- 2017 -

 

141.  J. Am. Chem. Soc., 2017, 139 (49), pp 18009–18015: “Allosteric modulation of Grb2 recruitment to the intrinsically unstructured scaffold protein, LAT, by remote site phosphorylation”, William Y. C. Huang, Jonathon A. Ditlev, Han-Kuei Chiang, Michael K. Rosen*, Jay T. Groves*.

 

140.  Proc. Natl. Acad. Sci. USA 2017, 114, 46: 12190-12195: “Early T cell receptor signals globally modulate ligand-receptor affinities during antigen discrimination”, Rafal M. Pielak, Geoff P. O’Donoghue, Jenny J. Lin, Kate Alfieri, Nicole C. Fay, Shalini T. Low-Nam, Jay T. Groves*.

 

139.  Biophys. J. 2017, 113: 1807-1813: “Dynamic scaling analysis of molecular motion within the LAT:Grb2:SOS protein network on membranes”, William Y. C. Huang, Han-Kuei Chiang, Jay T. Groves*.

 

138.  eLife, 2017, 6: e25885: “Two-step membrane binding by the bacterial SRP receptor enable efficient and accurate Co-translational protein targeting”, Yu-Hsien Hwang Fu, William Y. C. Huang, Kuang Shen, Jay T. Groves, Thomas Miller, Shu-ou Shan*

 

137. Adv. Healthcare Mater. 2017, 1700243: “Dynamic cellular interactions with extracellular matrix triggered by biomechanical tuning of low-rigidity supported lipid membranes”, Setareh Vafaei, Seyed R. Tabaei, Kabir H. Biswas, Jay T. Groves, and Nam-Joon Cho*.

 

136. Nature Comm. 2017, 8: 156061: “Mechanism of SOS PR-domain autoinhibition revealed by single-molecule assays on native protein from lysate”. Young Kwang Lee, Shalini T. Low-Nam, Jean K. Chung, Scott D. Hansen, Hiu Yue Monatrice Lam, Steven Alvarez, Jay T. Groves*.

 

     See also:

          Genetic Engineering and Biotechnology News

          December 2017

          GENengnews.com

 

- 2016 -

 

135. Biophys. J. 2016, 1044-1052: “Sustained α-catenin conformational activation at E-cadherin junctions in the absence of mechanical force”, Kabir H Biswas*, Kevin L Hartman, Ronen Zaidel-Bar*, Jay T. Groves*.

 

134. Nano Lett. 2016, 16, 8: 5022-5026: “Graphene-templated supported lipid membrane nanochannels”, Wan Li, Jean K. Chung, Young Kwang Lee, Jay T. Groves*.

 

133. Nat. Struct. Molec. Biol. 2016, 23, 9: 838-846: “One-way membrane trafficking of SOS in receptor-triggered Ras activation”, Sune M. Christensen, Hsiung-Lin Tu, Jesse Jun, Steven Alvarez, Meredith Triplet, Jeffrey S. Iwig, Kamlesh Yadav, Dafna Bar-Sagi, Jeroen P. Roose*, and Jay T. Groves*.

 

132. Langmuir 2016, 32, 6775-6780: “A microbead supported membrane-based fluorescence imaging assay reveals intermembrane receptor−ligand complex dimension with nanometer precision”, Kabir H. Biswas* and Jay T. Groves*.

 

131. Proc. Natl. Acad. Sci. USA. 2016, 113, 29: 8218-8223: “Phosphotyrosine-mediated LAT assembly on membranes drives kinetic bifurcation in the recruitment dynamics of the Ras activator SOS”, William Y. C. Huang, Qingrong Yan, Wan-Chen Lin, Jean K. Chung, Scott D. Hansen, Sune M. Christensen, Hsiung-Lin Tua, John Kuriyan, and Jay T. Groves*.

 

130. Nanoscale. 2016, 8: 13513-13520: “Size-dependent, stochastic nature of lipid exchange between nano-vesicles and model membranes”, Seyed R. Tabaei, Jurriaan J. J. Gillissen, Setareh Vafaei, Jay T. Groves, and Nam-Joon Cho*.

 

129. Nano Letters. 2016, 16, 2890-2895: "Monitoring the waiting time sequence of single Ras GTPase activation events using liposome functionalized zero-mode waveguides". Sune M. Christensen, Meredith G. Triplet, Christopher Rhodes, Jeffrey S. Iwig, Hsiung-Lin Tu, Dimitrios Stamou, and Jay T. Groves*.

 

128. J. Am. Chem. Soc. 2016, Jan 26: "Covalent Ras Dimerization on Membrane Surfaces through Photosensitized Oxidation". Jean K. Chung, Young Kwang Lee, Hiu Yue Monatrice Lam, and Jay T. Groves*.

 

127. J. Phys. Chem B 2016, Jan 15: "Dynamic Organization of Myristoylated Src in the Live Cell Plasma Membrane", Adam W. Smith*, Hector H. Huang, Nicholas F. Endres, Christopher Rhodes, and Jay T. Groves*.

 

126. Biophys. J. 2016, 110, 176-187: "Cholesterol-Enriched Domain Formation Induced by Viral-Encoded, Membrane-Active Amphipathic Peptide", Joshua M. Hanson, Douglas L. Gettel, Seyed R. Tabaei, Joshua Jackman, Min Chul Kim, Darryl Y. Sasaki, Jay T. Groves, Bo Liedberg, Nam-Joon Cho, and Atul N. Parikh*.

 

- 2015 -

 

125. Mol. Biol. Cell 2015, Nov 5; 26(22), 4033-4045: "Diffusion of GPI-linked proteins is influenced by the activity of dynamic cortical actin", Suvrajit Saha, Il-Hyung Lee, Anirban Polley, Jay T Groves, Madan Rao, Satyajit Mayor*.

 

124. Proc. Natl. Acad. Sci USA 2015, Dec 29; 112(52), 15892-15897: "Negative membrane curvature catalyzes nucleation of endosomal sorting complex required for transport (ESCRT)-III assembly", Il-Hyung Lee, Hiroyuki Kai, Lars-Anders Carlson, Jay T. Groves, and James H. Hurley*.

 

123. Proc. Natl. Acad. Sci USA 2015, Sep 1;112(35):10932-7: "E-cadherin junction formation involves an active kinetic nucleation process", Kabir H. Biswas, Kevin L. Hartman, Cheng-Han Yu, Oliver J. Harrison, Hang Song, Adam W. Smith, William Y. C. Huang, Wan-Chen Lin, Zhenhuan Guo, Anup Padmanabhan, Sergey M. Troyanovsky, Michael L. Dustin, Lawrence Shapiro, Barry Honig, Ronen Zaidel-Bar, and Jay T. Groves*.

 

122. eLife 2015, Mar 6;4: "Importin-β modulates the permeability of the nuclear pore complex in a Ran-dependent manner", Alan R. Lowe, Jeffery H. Tang, Jaime Yassif, Michael Graf, William Y. C. Huang, Jay T. Groves, Karsten Weis*, and Jan T Liphart*.

 

121. J. Phys. Chem B 2015, Mar 26;119(12):4450-9: "Live cell plasma membranes do not exhibit a miscibility phase transition over a wide range of temperatures", II-Hyung Lee, Suvrajit Saha, Anirpan Polley, Hector Huang, Satyajit Mayor, Madan Rao, and Jay T. Groves*.

 

- 2014 -

 

120. Science 2014, 345, 50-54: "Ras activation by SOS: Allosteric regulation by altered fluctuation dynamics", Lars Iversen1, Hsiung-Lin Tu1, Wan-Chen Lin, Sune M. Christensen, Steven M. Abel, Jeff Iwig, Hung-Jen Wu, Jodi Gureasko, Christopher Rhodes, Rebecca S. Petit, Scott D. Hansen, Peter Thill, Cheng-Han Yu, Dimitrios Stamou, Arup K. Chakraborty, John Kuriyan, and Jay T. Groves*.

 

119. Biophysical Journal 2014, 106, 2196-2205: "Spatial Organization of EphA2 at the Cell-Cell Interface Modulates Trans-Endocytosis of EphrinA1", Adrienne C. Greene1, Samuel J. Lord1, Aiwei Tian, Christopher Rhodes, Hiroyuki Kai, and Jay T. Groves*.

 

118. Nano Lett. 2014, 14, 2293-2298: "Size-based chromatography of signaling clusters in a living cell membrane", Niña G. Caculitan1, Hiroyuki Kai1, Eulanca Y. Liu1, Nicole Fay, Yan Yu, Theobald Lohmüller, Geoff P. O’Donoghue, and Jay T. Groves*.

 

See also:

Highlighted on Nature Chemical Biology

 

117. Proc. Natl. Acad. Sci USA 2014, 111, 2996-3001: "H-Ras forms dimers on membrane surfaces via a protein-protein interface", Wan-Chen Lin1, Lars Iversen1, Hsiung-Lin Tu, Christopher Rhodes, Sune M. Christensen, Jeffrey S. Iwig, Scott D. Hansen, William Y. C. Huang, and Jay T. Groves*.

 

116. eLife 2014, 3:e01610: "Activation-triggered subunit exchange between CaMKII holoenzymes facilitates the spread of kinase activity" Margaret M. Stratton1, Il-Hyung Lee1, Moitrayee Bhattacharyya, Sune M. Christensen, Luke H. Chao, Howard Schulman, Jay T. Groves*, and John Kuriyan*.

 

- 2013 -

 

115. Biophys. J. 2013, 105, L11: "Ratiometric Imaging of the T-Cell Actin Cytoskeleton Reveals the Nature of Receptor-Induced Cytoskeletal Enrichment", Alexander A. Smoligovets, Adam W. Smith, and Jay T. Groves*.

 

114. eLife 2013, 2, e00778: "Direct single molecule measurement of TCR triggering by agonist pMHC in living primary T cells", Geoff P. O’Donoghue1, Rafal M. Pielak1, Alexander A. Smoligovets, Jenny J. Lin, and Jay T. Groves*.

 

See also:

Research Highlight in Nature Immunology "TCRs go it alone"

 

113. Nano Lett. 2013, 13, 3059-3064: "Nanoscale Obstacle Arrays Frustrate Transport of EphA2 – Ephrin-A1 Clusters in Cancer Cell Lines", Theobald Lohmüller, Qian Xu, and Jay T. Groves*.

 

See also:

LBNL News Center, July 1, 2013.

 

112. J. Cell Sci., 2013, 126, 1049-1058: "Modulation of T cell signaling by the actin cytoskeleton", Yan Yu, Alexander A. Smoligovets, and Jay T. Groves*.

 

111. J. Am. Chem. Soc., 2013, 135, 5012‐5016: "DNA-mediated assembly of protein heterodimers on membrane surfaces", Michael P. Coyle, Qian Xu, Samantha Chiang, Matthew B. Francis*, Jay T. Groves*.

 

110. Nature Materials, 2013, 12, 96-97: "Cell membranes: Glycans' imprints", Jay T. Groves*.

 

109. Cell, 2013, 152, 543-556: "Conformational coupling across the plasma membrane in activation of the EGF receptor", Nicholas F. Endres, Rahul Das, Adam Smith, Anton Arkhipov, Erika Kovacs,Yongjian Huang, Jeffrey G. Pelton, Yibing Shan, David E. Shaw, David E. Wemmer, Jay T. Groves*, and John Kuriyan*.

 

- 2012 -

 

108. Nat. Methods., 2012, 9, 1189-1191: "Membrane-protein binding measured with solution-phase plasmonic nanocube sensors.", Hung-Jen Wu, Joel Henzie, Wan-Chen Lin, Christopher Rhodes, Zhu Li, Elodie Sartorel, Jeremy Thorner, Peidong Yang, and Jay T Groves*.

 

107. J. Am. Chem. Soc., 2012, 134(26), 10833-10842: "Monitoring Lipid-Anchor Organization in Cell Membranes by PIE-FCCS.", Sara B. Triffo, Hector H Huang, Adam W Smith, Eldon T Chou, and Jay T Groves*.

 

106. J. Am. Chem. Soc., 2012, 134(23), 9549-9552: "Investigating cell surface galectin-mediated cross-linking on glycoengineered cells.", Brian Belardi, Geoff P. O'Donoghue, Adam W. Smith, Jay T. Groves, and Carolyn R. Bertozzi*.

 

105. J. Phys. Chem. B, 2012, 116(17), 5122-5131: "Single molecule kinetics of ENTH binding to lipid membranes.", Sharon Rozovsky, Martin B. Forstner, Holger Sondermann, and Jay T. Groves*.

 

104. Annu. Rev. Biophys., 2012, 41, 543-56:"Receptor signaling clusters in the immune synapse.", Michael L. Dustin* and Jay T. Groves*.

 

103. J. Phys. Chem. B, 2012, 116(11), 3630-3640: "The membrane environment can promote or suppress bistability in cell signaling networks.", Steven M. Abel, Jeroen P. Roose, Jay T. Groves, Arthur Weiss, and Arup K. Chakraborty*.

 

102. Nano Lett., 2012, 12(3), 1717-1721: "Single molecule tracking on supported membranes with arrays of optical nanoantennas.", T. Lohmüller, L. Iversen, M. Schmidt, C. Rhodes, H.-L. Tu, W.-C. Lin, and Jay T. Groves*.

 

See also:

LBNL news center, March 23, 2012

 

101. J. Cell Sci., 2012, 125(3), 735-42: "Characterization of dynamic actin associations with T-cell receptor microclusters in primary T cells.", Alexander A. Smoligovets, Adam W. Smith, Hung-Jen Wu, Rebecca S. Petit, Jay T. Groves*.

 

100. PloS ONE, 2012, 7(2), e30704: "Myosin IIA Modulates T Cell Receptor Transport and CasL Phosphorylation during Early Immunological Synapse Formation.", Yan Yu, Nicole C. Fay, Alexander A. Smoligovets, Hung-Jen Wu, Jay T. Groves*.

 

 - 2011 -

 

99. Biophys. J., 2011, 101(11), 2731-2739,"EphA2 Receptor Activation by Monomeric Ephrin-A1 on Supported Membranes.", Qian Xu, Wan-Chen Lin, Rebecca S. Petit, and Jay T. Groves*.

 

98. Nano Lett., 2011, 11(11), 4912-4918,"Supported Membranes Embedded with Fixed Arrays of Gold Nanoparticles.", Theobald Lohmüller, Sara Triffo, Geoff P. O'Donoghue, Qian Xu, Michael P. Coyle, and Jay T. Groves*.

 

See also:

LBNL news center, October 31, 2011

 

97. Cell, 2011, 146(5), 732-745: "A Mechanism for Tunable Autoinhibition in the Structure of a Human Ca2+/Calmodulin- Dependent Kinase II Holoenzyme.", Luke H. Chao, Margaret M. Stratton, Il-Hyung Lee, Oren S. Rosenberg, Joshua Levitz, Daniel J. Mandell, Tanja Kortemme, Jay T. Groves, Howard Schulman and John Kuriyan*.

 

See also:

Video abstract from Cell PaperFlick

 

96. Curr. Opin. Cell Biol., 2011, 23(4), 370-376: "Signaling clusters in the cell membrane.", Niña C Hartman, Jay T Groves*.

 

See also:

Featured as Cover Figure!

Featured on Antibody Resource

 

95. PNAS, 2011, 108(22), 9089-909: "T-cell triggering thresholds are modulated by the number of antigen within individual T-cell receptor clusters.", Boryana N. Manz, Bryan L. Jackson, Rebecca S. Petit, Michael L. Dustin and Jay Groves*.

 

94. Nat. Protoc., 2011, 6, 523-539: "Using patterned supported lipid membranes to investigate the role of receptor organization in intercellular signaling.", Pradeep M. Nair, Khalid Salaita, Rebecca S. Petit and Jay T. Groves*.

 

93. J. Phys. Chem. A, 2011, 115(16), 3867-3875: "Patterned Two-Photon Photoactivation Illuminates Spatial Reorganization in Live Cells.", Adam W. Smith, Alexander A. Smoligovets, and Jay T. Groves*.

 

 - 2010 -

 

92. Current Protocols in Chemical Biology, 2010, 2:235-269: "Supported Membrane Formation, Characterization, Functionalization, and Patterning for Application in Biological Science and Technology.", Wan-Chen Lin, Cheng-Han Yu, Sara Triffo, Jay T. Groves*.

 

91. Communicative & Integrative Biology, 2010, 3:5, 454-457: "Roles of the cytoskeleton in regulating EphA2 signals.", Khalid Salaita and Jay T. Groves*.

 

90. PNAS, 2010, 107, 19213-19218: "Engineering of a synthetic electron conduit in living cells.", Heather M. Jensen, Aaron E. Albers, Konstantin R. Malley, Yuri Y. Londer, Bruce E. Cohen, Brett A. Helms, Peter Weigele, Jay T. Groves, Caroline M. Ajo-Franklin*.

*

89. Med. Biol. Eng. Comput., 2010, 48(10): "Engineering supported membranes for cell biology.", Cheng-Han Yu, Jay T. Groves*.

 

88. New J. Phys., 2010, 12 095001: "Bending-mediated superstructural organizations in phase-separated lipid membranes.", Yoshihisa Kaizuka, Jay T. Groves*.

 

87. PLoS ONE, 2010, 5, e11878: "Altered Actin Centripetal Retrograde Flow in Physically Restricted Immunological Synapses.", Cheng-han Yu, Hung-Jen Wu, Yoshihisa Kaizuka, Ronald D. Vale, Jay T. Groves*.

 

86. Nat. Struct. Mol. Biol., 2010, 17, 659-665: "Molecular mechanisms in signal transduction at the membrane", Jay T. Groves* and John Kuriyan*.

 

85. Nat. Rev. Mol. Cell Biol., 2010, 11(5), 342-352: "Spatial organization and signal transduction at intercellular junctions", Boryana N. Manz and Jay T. Groves*.

 

See also:

Featured in Signaling-gateway_Immunology

Featured in Signaling-gateway_Techniques

 

84. Science, 2010, 327, 1380: "Restriction of receptor movement alters cellular response: physical force sensing by EphA2", Khalid Salaita1, Pradeep M. Nair1, Rebecca S. Petit, Richard M. Neve, Debopriya Das, Joe W. Gray, and Jay T. Groves*.

 

See also:

Perspective in Science, 2010, 327, 1335

HHMI News

Berkeley Lab News Center, March 11, 2010

The Daily Californian, Wednesday March 17, 2010

National Cancer Institute, Physical Sciences in Oncology Research News

Nat. Rev. Mol. Cell Biol., 2010, "Mechanotransduction: Using the force", Debbie Walker.

The Straits Times, June 5 2010, p. D11

 

83. Nat. Immuno., 2010, 11(1), 90-96 :  "TCR and LAT occur in separate domains on T cell membranes, which concatenate during activation", Bjorn F. Lillemeier, Manuel A. Mortelmaier, Martin B. Forstner, Johannes B. Huppa, Jay T. Groves, and Mark M. Davis*.

 

- 2009 -

 

82. Nat. Chem. Biol., 2009, 5(11), 783-784:  "The physical chemistry of membrane curvature", Jay T. Groves*.

 

81. J. Struct. Biol., 2009, 168(1):1-2.  Epub 2009:  "Supported membranes in structural biology", LK Tamm and JT Groves*.

 

80. PNAS, 2009, 106(31), 12729-12734: "Cluster size regulates protein sorting in the immunological synapse", Niña C. Hartman, Jeffrey A. Nye, Jay T. Groves*.

 

79. Nano Lett, 2009, 5, 2077-2082: "A nanocube plasmonic sensor for molecular binding on membrane surfaces", William J. Galush, Sarah A. Shelby, Martin J. Mulvihill, Andrea Tao, Peidong Yang, Jay T. Groves*.

 

78. Langmuir, 2009, 25(6), 3713-3717: "Effect of Support Corrugation on Silica Xerogel-Supported Phase-Separated Lipid Bilayers", Emel I. Goksu, Barbara A. Nellis, Wan-Chen Lin, Joe H. Satcher, Jr., Jay T. Groves, Subhash H. Risbud, Marjorie L. Longo*.

 

77. Soft Matter, 2009, 5, 1931-1936: "Like-charge interactions between colloidal particles are asymmetric with respect to sign", Esther W. Gomez, Nathan G. Clack, Hung-Jen Wu and Jay T. Groves*.

 

- 2008 -

 

76. ChemPhysChem,2008, 9, 12, 1688-1692: "Discrete Arrays of Liquid Crystal-Supported Proteolipid Monolayers as Phantom Cell Surfaces", Amber R. Wise, Jeffrey A. Nye, Jay T. Groves*.

 

75. Nat. Biotech., 2008, 26, 7, 825 - 830: "Electrostatic readout of DNA microarrays with charged microspheres", Nathan G. Clack, Khalid Salaita and Jay T. Groves*.

 

See also:

LBNL News.

C&ENews.

Nature Materials.

 

74. Annu. Rev. Biomed. Eng., 2008, 10, 311-338: "Fluorescence Imaging of Membrane Dynamics", Jay T. Groves*, Raghuveer Parthasarathy, Martin B. Forstner.

 

73. Biophys. J., 2008, 95, 2512-2519: "Quantitative fluorescence microscopy using supported lipid bilayer standards", William J. Galush, Jeffrey A. Nye and Jay T. Groves*.

 

72. Nat. Struct. Mol. Biol., 2008, 15, 452-461: "Membrane-dependent signal integration by the Ras activator Son of sevenless", Jodi Gureasko, William J. Galush, Sean Boykevisch, Holger Sondermann, Dafna Bar-Sagi, Jay T. Groves* and John Kuriyan*.

 

See also:

NSMB News and Views.

 

71. Langmuir, 2008, 24, 10, 6189-6193: "Electrical manipulation of supported lipid membranes by embedded electrodes", Bryan L. Jackson, Jeffrey A. Nye and Jay T. Groves*.

 

70. J. Am. Chem. Soc., 2008, 130, 18, 5947-5953: "Non-covalent cell surface engineering: incorporation of bioactive synthetic glycopolymers into cellular membranes", David Rabuka, Martin B. Forstner, Jay T. Groves and Carolyn R. Bertozzi*.

 

69. Langmuir, 2008, 24, 8, 4145 - 4149: "Kinetic control of histidine-tagged protein surface density on supported lipid bilayers", Jeffrey A. Nye and Jay T. Groves*.

 

68. Biophys. J., 2008, 94, 3286 - 3292: "T cell receptor microcluster transport through molecular mazes reveals mechanism of translocation", Andrew L. DeMond, Kaspar D. Mossman, Toby Starr, Michael L. Dustin and Jay T. Groves*.

 

- 2007 -

 

67. Current Opinion in Immunology, 2007, 19, 6, 722 - 727: "Interrogating the T cell synapse with patterned surfaces and photoactivated proteins", Andrew L. DeMond and Jay T. Groves*.

    Journal Request a Reprint

 

66. Proc. Natl. Acad. Sci. USA, 2007, 104, 51, 20332 - 20337: "A chemical approach to unraveling the biological function of the glycosylphosphatidylinositol anchor", Margot G. Paulick, Martin B. Forstner, Jay T. Groves* and Carolyn R. Bertozzi*.

    Journal Request a Reprint

 

65. J. Phys. Chem. B, 2007, 111, 12133 - 12135: "Molecular orientation of membrane-anchored mucin glycoprotein mimics", Raghuveer Parthasarathy, David Rabuka, Carolyn R. Bertozzi and Jay T. Groves*.

    Journal Request a Reprint

 

64. J. Am. Chem. Soc., 2007, 129, 11543 - 11550: "Synthetic analogues of glycosylphosphatidylinositol-anchored proteins and their behavior in supported lipid bilayers", Margot G. Paulick, Amber R. Wise, Martin B. Forstner, Jay T. Groves, and Carolyn R. Bertozzi*.

    Journal Request a Reprint

 

63. Annu. Rev. Phys. Chem., 2007, 58, 697 - 717: "Bending mechanics and molecular organization in biological membranes", Jay T. Groves.

    Journal Request a Reprint

 

62. J. Am. Chem. Soc., 2007, 129, 5462 - 5471: "Hierarchical assembly of model cell surfaces: Synthesis of mucin mimetic polymers and their display on supported bilayers", David Rabuka, Raghuveer Parthasarathy, Goo Soo Lee, Xing Chen, Jay T. Groves and Carolyn R. Bertozzi*.

    Journal Request a Reprint

 

61. Nature Prot., 2007, 2, 1438 - 1444: "Detection of proteins using a colorimetric bio-barcode assay", Jwa-Min Nam, Kyung-Jin Jang and Jay T. Groves*.

    Journal Request a Reprint

 

60. Langmuir, 2007, 23, 4, 2052 - 2057: "Hybrid Protein-Lipid Patterns from Aluminum Templates", Bryan L. Jackson and Jay T. Groves*.

    Journal Request a Reprint

 

59. Chem. Soc. Rev., 2007, 35, 1, 46 - 54: "Micropatterned supported membranes as tools for quantitative studies of the immunological synapse", Kaspar Mossman and Jay T. Groves*.

    Journal Request a Reprint

 

58. Soft Matt., 2007, 1, 1, 24 - 33: "Curvature and spatial organization in biological membranes", Raghuveer Parthasarathy and Jay T. Groves.

    Journal Request a Reprint

 

 - 2006 -

 

57. J. Am. Chem. Soc., 2006, 128, 48, 15354 - 15355: "Control of antigen presentation with a photoreleasable agonist peptide", Andrew L. DeMond, Toby Starr, Michael L. Dustin, and Jay T. Groves*.

    Journal Request a Reprint

 

56. Biophys. J., 2006, 91, 3600 - 3606: "Analysis of shape, fluctuations, and dynamics in intermembrane junctions", Lawrence C.-L. Lin, Jay T. Groves, and Frank L. H. Brown*.

    Journal Request a Reprint

 

55. Science, 2006, 313: 1901-1902: "Unveiling the membrane domains", Jay T Groves*.

    Journal Request a Reprint

 

54. J. Am. Chem. Soc., 2006, 128, 47, 15221 - 15227: "Lipid lateral mobility and membrane phase structure modulation by protein binding" Martin B. Forstner, Chanel K. Yee, Atul N. Parikh, Jay T. Groves*.

    Journal Request a Reprint

 

53. Curr. Op. Chem. Biol., 2006, 10, 544 - 550: "Spatial mutation of the T cell immunological synapse" Jay T. Groves*.

    Journal Request a Reprint

 

52. Langmuir, 2006, 22, 12, 5374 - 5384: "Nonequilibrium patterns of cholesterol-rich chemical heterogenieties within single fluid supported phospholipid bilayer membranes", Annapoorna R. Sapuri-Butti, Qijuan Li, Jay T. Groves, and Atul N. Parikh*.

    Journal Request a Reprint

 

51. Langmuir, 2006, 22, 5095 - 5099: "Curvature-modulated phase separation in lipid bilayer membranes", Raghuveer Parthasarathy, Cheng-Han Yu and Jay T. Groves*.

    Journal Request a Reprint

 

50. J. Phys. Chem. B, 2006, 110, 8513-8516: "Coupled membrane fluctuations and protein mobility in supported inter-membrane junctions", Raghuveer Parthasarathy and Jay T. Groves*.

    Journal Request a Reprint

 

49. Phys. Rev. Lett., 2006, 96, 118101: "Hydrodynamic damping of membrane thermal fluctuations near surfaces imaged by fluorescence interference microscopy", Yoshihisa Kaizuka and Jay T. Groves*.

    Journal Download data sets Request a Reprint

 

48. ChemBioChem, 2006, 7, 436-440: "A Fluid Membrane-Based Soluble Ligand Display System for Live Cell Assays", Jwa-Min Nam, Pradeep M. Nair, Richard M. Neve, Joe W. Gray, and Jay T. Groves*.

    Journal Request a Reprint

 

47. Anal. Chem., 2006, 78, 174-180: "Surface binding affinity measurements from order transitions of lipid membrane-coated colloidal particles", Esther M. Winter, and Jay T. Groves*.

    Journal Request a Reprint

 

 - 2005 -

 

46. Science, 2005, 310, 1191 - 1193: "Altered TCR Signaling from Geometrically Repatterned Immunological Synapses", Kaspar D. Mossman, Gabriele Campi, Jay T. Groves* and Michael L. Dustin*.

    Journal Request a Reprint

 

See also:

LBL News.

MIT Technology Review.

JCB Research Roundup.

Nat. Chem. Biol. Research Highlights.

 

45. Science STKE, 2005, 301: pe45. "Learning the Chemical Language of Cell- Surface Interactions", Jay T. Groves*.

    Journal Request a Reprint

 

44. Langmuir, 2005, 21, 23, 10693 - 10698: "Neuronal Activation by GPI-linked Neuroligin-1 Displayed in Synthetic Lipid Bilayer Membranes", Michael M. Baksh, Camin Dean, Sophie Pautot, Shannon DeMaria, Ehud Isacoff, and Jay T. Groves*.

    Journal Request a Reprint

 

43. Nat. Chem. Biol., 2005, 1, 283 - 289: "Molecular adhesion of the neuronal synapse reconstituted between live cells and supported lipid bilayer", Sophie Pautot, Hanson Lee, Ehud Y. Isacoff, and Jay T. Groves*.

 

42. J. Phys. Chem. B, 2005, 109, 42, 19960 - 19969: "Phase segregation on different length scales in a model cell membrane system: the formation and clustering of lipid rafts", Jian Liu, Shuyan Qi, Jay T. Groves and Arup K. Chakraborty*.

    Journal Request a Reprint

 

41. Anal. Chem., 2005, 77, 21, 6985 - 6988: "A Colorimetric Bio-Barcode Amplification Assay for Cytokines", Jwa-Min Nam, Amber R. Wise and Jay T. Groves.

    Journal Request a Reprint

 

40. J. Am. Chem. Soc., 2005, 127, 41, 14383-14387: "Synthesis of lipidated green fluorescent protein and its incorporation in supported lipid bilayers", Michael J. Grogan, Yoshihisa Kaizuka, Rosemary M. Conrad, Jay T. Groves*, and Carolyn R. Bertozzi*.

    Journal Request a Reprint

 

39. BioMEMS and Biomedical Nanotechnology, Vol. III, 2005, Ch. 17, p. 295 - 310: "Supported lipid bilayers as mimics for cell surfaces", Jay T. Groves*.

 

38. Phys. Rev. Lett., 2005, 95, 048101: "Electrostatically driven spatial patterns in lipid membrane composition", Raghuveer Parthasarathy, Paul A. Cripe and Jay T. Groves*.

    Journal Request a Reprint

 

37. Langmuir, 2005, 21, 6430-6435: "Many-particle tracking with nanometer resolution in three dimensions by reflection interference contrast microscopy", Nathan Clack and Jay T. Groves*.

    Journal Request a Reprint

 

36. BMC Biotechnology, 2005, 5, 18: "Cell membrane array fabrication and assay technology", Victoria Yamazaki, Oksana Sirenko, Robert J Schafer, Luat Nguyen, Thomas Gutsmann, Lore Brade and Jay T Groves.

    Journal Request a Reprint

 

35. Adv. Mater., 2005, 17, 1477-1480: "Direct Patterning of Membrane-Derivatized Colloids Using in situ UV-Ozone Photolithography", Cheng-Han Yu, Atul N. Parikh, and Jay T. Groves*.

    Journal Request a Reprint

 

34. J. Am. Chem. Soc., 2005, 127, 5, 2826-2827: "Lipid mobility and molecular binding in fluid lipid membranes", Victoria Yamazaki, Oksana Sirenko, Robert J. Shafer and Jay T. Groves*.

    Request a Reprint

 

33. Angew. Chem. Int. Ed., 2005, 44, 3524-3538: "Molecular Organization and Signal Transduction at Intermembrane Junctions", Jay T. Groves*.

    Journal Request a Reprint

 

32. J. Am. Chem. Soc., 2005, 127, 1, 36-37: "Formation and spatio-temporal evolution of periodic structures in lipid bilayers", Sharon Rozovsky, Yoshihisa Kaizuka and Jay T. Groves*.

    Journal Request a Reprint

 

- 2004 -

 

31. J. Am. Chem. Soc., 2004, 126, 43, 13878-13879: "Scanning probe lithography on fluid lipid membranes", Bryan L. Jackson and Jay T. Groves*.

    Journal Request a Reprint

 

30. Proc. Natl. Acad. Sci. USA, 2004, 101, 35, 12798-12803: "Protein patterns at lipid bilayer junctions", Raghuveer Parthasarathy and Jay T. Groves*.

    Journal Request a Reprint

 

29. Cell Biochem. Biophys., 2004, 41, 391-414: "Optical techniques for imaging membrane topography", Raghuveer Parthasarathy and Jay T. Groves*.

    Journal Request a Reprint

 

28. Nature, 2004, 427, 139-141: "Detection of molecular interactions at membrane surfaces through colloid phase transitions", Michael M. Baksh, Michal Jaros, and Jay T. Groves*.

    Journal Request a Reprint

    See also accompanying News and Views article.

    See also column in the March 2004 issue of Biophotonics International.

    See also highlight review by Claudia Steinem and Andreas Janshoff. Chem Phys Chem,

    2004, 5, 1121-1124.

    See also highlight by Katie Cottingham. Anal Chem, 2004, 76, 19, 368A.

 

   27. Biophys. J., 2004, 86, 905-912: "Structure and dynamics of supported intermembrane junctions", Yoshihisa Kaizuka and Jay T. Groves*.

    Journal Request a Reprint

 

   26. J. Phys. Chem. B, 2004, 108, 649-657: "Nonequilibrium adhesion patterns at lipid bilayer junctions", Raghuveer Parthsarathy, Bryan L. Jackson, Thomas J. Lowery, Amy P. Wong and Jay T. Groves*.

    Journal Request a Reprint

 

- 2003 -

 

25. J. Immunol. Meth., 2003, 19-32: "Supported planar bilayers in studies on immune cell adhesion and communication", Jay T. Groves* and Michael Dustin.

    Request a Reprint

 

24. Langmuir, 2003, 19, 1606-1610: "Electrostatically-targeted intermembrane lipid exchange with micropatterned supported membranes", Annapoorna R. Sapuri, Michael M. Baksh and Jay T. Groves*.

    Journal Request a Reprint

 

- 2002 -

 

23. Proc. Natl Acad. Sci. USA, 2002, 99, 22, 14147-14152: "Molecular topography imaging by intermembrane fluorescence resonance energy transfer", Amy P. Wong and Jay T. Groves*.

    Journal Request a Reprint

 

22. TRENDS Immunology, 2002, 23, 10, 492-499: "Correlation of a dynamic model for immunological synapse formation with effector functions: two pathways to synapse formation", Sung-Joo Lee, Y. Hori, Jay T. Groves, Michael L. Dustin and Arup K. Chakraborty.

    Journal Request a Reprint

 

21. TRENDS Immunology, 2002, 23, 10, 500-502: "The synapse assembly model", Sung-Joo Lee, Y. Hori, Jay T. Groves, Michael L. Dustin and Arup K. Chakraborty*.

    Journal Request a Reprint

 

20. Europhys. Lett., 2002, 59, 6, 916-922: "Pattern formation during adhesion of multicomponent membranes", Thomas R. Weikl, Jay T. Groves* and Reinhard Lipowsky.

    Journal Request a Reprint

 

19. Curr. Op. DDD, 2002, 5, 4, 606-612: "Membrane array technology for drug discovery", Jay T. Groves*.

    Journal Request a Reprint

 

18. Business Briefing: Life Sciences Technology, 2002: "Integrated cell membrane-microchip technologies", Jay T. Groves*.

 

17. Acct. Chem. Res., 2002, 35, 149-157: "Micropattern formation in supported lipid membranes", Jay T. Groves* and Steven G. Boxer.

    Journal Request a Reprint

 

- 2001 -

 

16. J. Am. Chem. Soc., 2001, 123, 12414-12415: "Topographical imaging of an intermembrane junction by combined fluorescence interference and energy transfer microscopies", Amy P. Wong and Jay T. Groves*.

    Journal Request a Reprint

 

15. Langmuir, 2001, 17, 17, 5129-5133: "Control of cell adhesion and growth with micropatterned supported lipid membranes", Jay T. Groves, Lara K. Mahal and Carolyn R. Bertozzi.

    Journal Request a Reprint

 

14. Proc. Natl Acad. Sci. USA, 2001, 98, 12, 6548-6553: "Synaptic pattern formation during cellular recognition", S.Y. Qi, Jay T. Groves and Arup Chakraborty.

    Journal Request a Reprint

 

- 2000 -

 

13. J. Phys. Chem. B, 2000, 104, 11409-11415: "Lateral reorganization of fluid lipid membranes in response to the electric field produced by a buried charge", Jay T. Groves, Steven G. Boxer and Harden M. McConnell.

    Journal Request a Reprint

 

12. J. Phys. Chem. B, 2000, 104, 119-124: "Electric field effects in multicomponent fluid lipid membranes", Jay T. Groves, Steven G. Boxer and Harden M. McConnell.

    Journal Request a Reprint

 

11. Adv. Mater., 2000, 12, 10, 731-734: "Printing via photolithography on micropartitioned fluid lipid membranes", Li Kung, Jay T. Groves, Nick Ulman and Steven G. Boxer.

    Request a Reprint

 

- Before 2000 -

 

10. Langmuir, 1999, 15, 3893-3896: "Writing and erasing barriers to lateral diffusion in fluid membranes", Paul Cremer, Jay T. Groves, Li Kung and Steven G. Boxer.

    Journal Request a Reprint

 

9. Langmuir, 1998, 12, 14, 3347-3350: "Substrate-membrane interactions: mechanisms for imposing patterns on a fluid bilayer membrane", Jay T. Groves, Nick Ulman, Paul Cremer and Steven G. Boxer.

    Journal Request a Reprint

 

8. Proc. Natl Acad. Sci. USA, 1998, 95, 935-938: "Electric field-induced critical demixing in lipid bilayer membranes", Jay T. Groves, Steven G. Boxer and Harden M. McConnell.

    Journal Request a Reprint

 

7. Proc. Natl Acad. Sci. USA, 1997, 94, 13390-13395: "Electric field-induced reorganization of two-component supported bilayer membranes", Jay T. Groves, Steven G. Boxer and Harden M. McConnell.

    Journal Request a Reprint

 

6. Adv. Mater., 1997, 9, 14, 1121-1123: "Micropatterning fluid membranes", Nick Ulman, Jay T. Groves and Steven G. Boxer.

    Journal Request a Reprint

 

5. Science, 1997, 275, 651-653: "Micropatterning fluid lipid bilayers on solid supports", Jay T. Groves, Nick Ulman and Steven G. Boxer. See also: The Wall Street Journal, Jan. 31 1997, B1.

    Journal Request a Reprint

 

4. Biophys. J., 1996, 71, 2716-2723: "Electrical manipulation of glycan-phosphatidyl inositol-tethered proteins in planar supported bilayers", Jay T. Groves, Christoph W’[lfing and Steven G. Boxer.

    See also: Zasadzinski, Joseph A. "New and Notable" article pp 2243-2244, same issue.

    Journal Request a Reprint

 

3. Biochemistry, 1996, 35, 40, 14773-14781: "Architecture and function of membrane proteins in planar supported bilayers: a study with photosynthetic reaction centers", Joshua Salafsky, Jay T. Groves and Steven G. Boxer.

    Journal Request a Reprint

 

2. Biophys. J., 1996, 70, 1573-1574: "Chiral Discrimination in Two Dimensions", Jay T. Groves and Harden M. McConnell.

    Journal Request a Reprint

 

1. Biophys. J., 1995, 69, 1972-1975: "Electric field-induced concentration gradients in planar supported bilayers", Jay T. Groves and Steven G. Boxer.

    Journal Request a Reprint

 

 

 

* = corresponding author(s)

 

 

Patents

 

US 8,114,602 “Detection of molecular interactions” (Issued February 14, 2012)

 

US 6,699,719 "Biosensor arrays and methods" Filed: Jul. 22, 2002, Issued: Mar. 2, 2004

 

US 6,228,326 "Arrays of independently-addressable supported fluid bilayer membranes" Filed: Nov. 26, 1997, Issued: May 8, 2001

 

Lab Contact:

Lab Phone: (510) 666-3604

Office Phone: (510) 666-3602

Fax: (510) 666-3603

 

Also see Contact page.

Mailing Address:

University of California

Department of Chemistry

424 Stanley Hall, MC3220

Berkeley, CA 94720